髓细胞促进胶质瘤恶性进程的研究进展
Cancer Research and Clinic(2021)
Abstract
髓细胞是胶质瘤微环境的重要组成部分,其具有强大的机体免疫功能,主要由胶质瘤相关的小胶质细胞/巨噬细胞和髓源性抑制细胞构成。文章综述髓细胞促进胶质瘤恶性进展的机制,并整理了多条相关通路,为抗肿瘤靶向治疗提供了新的方向及思路。
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Key words
Glioma,Myeloid cells,Signal transduction
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