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Binding Mechanism between CrkII and cAbl Kinase

Keigo Ikezaki,Hiroshi Sekiguchi,Muneyo Mio,Tai Kubo,Yuji C. Sasaki,Debsindhu Bhowmik,Kurt W. Van Delinder,Eugene Mamontov,Hugh O’Neill,Qiu Zhang,Ahmet Alatas,Xiang-Qiang Chu,Xiaolin Cheng,Dean A. A. Myles,John Katsaras,Roman Agafonov,Elizabeth Donohue Vo,Katelyn Connell,Gabriel Mercado, Tad George,Frank McCormick,Dorothee Kern

semanticscholar（2017）

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Abstract
the binding patches that are scattered on the protein surface show that their distribution and growth will depend on the protein’s functional group. Finally, in several cases, the binding-site predictions resulting from the cross-docking simulations will lead to the identification of an alternate interface, which corresponds to the interaction with a biomolecular partner that is not included in the original benchmark. Ref: Vamparys et al. (2016), Proteins. doi:10.1002/prot.25086
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