Haemodynamic Effects of Subarachnoid Blockade: 2% Lignocaine Versus 0.5% Plain Bupivacaine
ANAESTHESIST(2000)
摘要
Background: Our study compared the haemodynamic changes after spinal anaesthesia with 2% lignocaine and 0,5% plain bupivacaine.Methods: A controlled, randomized trial was performed on 30 patients scheduled for arthroscopic knee surgery. 2% lignocaine and 0.5% plain bupivacaine were used for spinal anaesthesia. We measured cardiac output (electrical bioimpedance cardiography), blood pressure and development of sensory blockade before and for 25 minutes after spinal anaesthesia.Results: In patients developing a sensory block below T6 there were no differences between both anaesthetics in haemodynamic parameters. But in patients developing a sensory block at or above T6 there was a greater drop in mean arterial pressure and cardiac output and a faster decrease in heart rate for bupivacaine compared to patients receiving Lignocaine.Conclusion:ln patients developing a sensory block at or above the T6 dermatome, the decrease in cardiac output and mean arterial pressure in the first 25 min after spinal anaesthesia is smaller when 2% lignocaine rather than 0.5% bupivacaine is used for blockade.
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关键词
anaesthesia spinal,lignocaine,bupivacaine,cardiac output,cardiography impedance
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