Evaluation of arsenic species in leukocytes and granulocytes of acute promyelocytic leukemia patients treated with arsenic trioxide

Xinyu Wang, Zhao Qian,Haitao Li,Hongzhu Chen,Liwang Lin,Meihua Guo,Xin Hai

Journal of Pharmaceutical and Biomedical Analysis（2021）

引用 6|浏览8

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摘要

•A HPLC-ICP-MS method was developed for intracellular arsenic speciation.•Arsenic species in leukocyte and granulocyte were analyzed for the first time.•Distribution trend of arsenic species in leukocytes and granulocytes was clarified.

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关键词

Acute promyelocytic leukemia,Arsenic species,Leukocyte,Granulocyte,HPLC-ICP-MS

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