Biologically Active Substances in the Aqueous Fraction of Alfredia cernua (L.) Cass. Extract Possessing Antiamnesic Properties
PHARMACEUTICAL CHEMISTRY JOURNAL(2021)
摘要
The composition of biologically active substances in the aqueous total fraction of the 95% EtOH extract of the aerial part of Alfredia cernua (L.) Cass. possessing antiamnesic properties was studied using chromatographic and mass-spectrometric methods. The total amount of N-containing compounds in the fraction was found to be 10.63 ± 1.65%. Fifteen amino acids (1.99 ± 0.11%), seven of which (0.76 ± 0.012%) were essential and included lysine, threonine, valine, isoleucine, leucine, phenylalanine, and histidine, were identified using an amino-acid analyzer. The total fraction was dominated by glutamic and aspartic acids, valine, proline, alanine, and histidine. The composition included a total of 43 elements (1.35 ± 0.1%), of which 19 were essential or conditionally essential. The predominant elements were K, Mg, Zn, Rb, P, Ca, and Mn. Carbohydrates dominated (32 ± 3.1%) the fraction.
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关键词
qualitative composition,content,glutamic acid,K,Mg,Zn,Rb,HPLC,inductively-coupled plasma mass spectrometry,aerial part of Alfredia cernua
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