Hunting for human ribozymes
NATURE CHEMICAL BIOLOGY（2021）
摘要
n approach based on enrichment of 5′ hydroxylated RNAs reveals a new self-cleaving ribozyme that maps to a very long non-protein-coding RNA in simians. The ribozyme is active only among hominin sequences, suggesting a recent acquisition of the activity.
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关键词
Enzymes,Ribozymes,RNA,Chemistry/Food Science,general,Biochemical Engineering,Biochemistry,Cell Biology,Bioorganic Chemistry
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