Discovering biological efficacy of new thiadiazole as effective inhibitors of urease, glycation, and (DPPH) scavengers: Biochemical and in silico study

•New thiadiazole were designed and synthesized.•Several functional groups were endured.•Effective inhibitors of urease, glycation, and (DPPH) scavengers.•Compound 13 was found as the effective and lead molecule.•Molecular docking study was presented to explain numerous key binding interactions.