尿毒净液延缓慢性肾功能衰竭的机理探讨
PRACTICAL CLINICAL JOURNAL OF INTEGRATED TRADITIONAL CHINESE AND WESTERN MEDICINE（2005）
Abstract
目的:研究尿毒净液对5/6肾切除鼠慢性肾功能不全模型的疗效及其作用机理.方法:建立5/6肾切除大鼠慢性肾功能不全模型,观察12周内尿毒净液和洛丁新对尿素氮、肌酐、24h尿蛋白量及肾小球平均截面积的影响.结果:尿素净液组和洛丁新组尿素氮、肌酐明显低于对照组,尿蛋白量低于对照组,尿毒净液组肾小球平均截面积均显著低于模型对照组和洛丁新组.结论:尿毒净液能改善5/6肾切除大鼠的肾功能.
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