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P2X7受体与年龄相关性黄斑变性

Leshu DAI,Shihui WANG,Jiantao SONG

Chinese Journal of Chinese Ophthalmology（2017）

Cited 8|Views8
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Abstract
年龄相关性黄斑变性(AMD)是中老年人致盲的重要原因,患病率高,其发病与多种因素有关,具体机制仍未完全明了.P2X7受体(P2X7R)是视网膜上表达的ATP门控阳离子通道,最近研究显示P2X7受体参与了AMD病理过程,本文对P2X7受体在AMD生理病理过程中的作用进行了讨论.
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Key words
age-related macular degeneration (AMD),purinergic ligand-gated ion channel 7 receptor (P2X7R),adenosine triphosphate (ATP),review
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