原发性肝癌患者血清微囊藻毒素水平与TNM分期的关联及对患者预后的影响
Chinese Journal of Surgery of Integrated Traditional and Western Medicine(2019)
Abstract
目的:探讨原发性肝癌(HCC)患者血清微囊藻毒素(MC-LR)水平与患者临床分期及预后之间的关系.方法:通过ELISA法检测HCC患者血清MC-LR水平,并分析HCC患者血清MC-LR水平与临床特征及预后之间的关联.结果:HCC患者血清MC-LR中位数为0.69 ng/mL,不同临床分期HCC患者血清MC-LR水平分布有差异(P<0.001),且呈线性相关(P<0.001);血清MC-LR水平与HCC患者年龄(P<0.01)、性别(P<0.05)、饮酒(P<0.05)、临床分期(P<0.001)、淋巴结转移(P<0.001)、远端转移(P<0.01)及HBV感染(P<0.05)相关,血清MC-LR水平越高,其生存期越短(P<0.05).结论:血清MC-LR水平与HCC患者预后相关,血清MC-LR水平越高患者生存期越短.
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