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益生菌治疗溃疡性结肠炎的研究进展

Kai FANG,Yi-zhou WANG,Hui WANG,Chang-lin ZHOU

Chinese Journal Of Pharmaceutical Biotechnology（2014）

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Abstract
溃疡性结肠炎(Ulcerative colitis,UC)是一种发病机制不明的肠道慢性炎症性疾病,病变主要累及结肠和直肠,容易反复发作,临床治疗效果不佳,故被列为现代顽疾之一.近年来,多数学者认为UC的发病可能与肠道粘膜免疫紊乱以及肠道菌群失调有关,所以利用肠道共生菌群特别是益生菌调节肠道内稳态治疗溃疡性结肠炎是目前研究热点之一.该文对益生菌治疗溃疡性结肠炎及其作用机制作综述.
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Key words
Ulcerative colitis,Dysbacteriosis,Probiotics,Effect of treat,Mechanisms,Research prospect
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