丙种球蛋白治疗川崎病的临床应用价值探讨
THE JOURNAL OF MEDICAL THEORY AND PRACTICE（2002）
Abstract
目的:探讨丙种球蛋白(ⅣIG)治疗川崎病的临床应用价值.方法:ⅣIG组给予IVIG400mg@kg-1@d-1,连用5d,加阿司匹林50mg@kg-1@d-1,热退后减至5mg@kg-1@d-1;常规组单用阿司匹林50mg@kg1@d-1,热退后减至5mg@kg1@d-1.结果:ⅣIG组冠状动脉病变发生率明显低于常规组(P＜0.05),发热,结膜,口腔充血,手足硬肿,淋巴结肿大消退时间皆比常规治疗组明显缩短,有非常显著差异(P＜0.01).结论:诊断川崎病后IVIG宜早用,注射剂量及使用时间以400mg@kg-1@d-1连用5d为宜.
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