Resistance Training, Regardless Of Protein Supplementation, Improves Muscular Phenotypes In Women Long-term After Bariatric Surgery: 2374 Board #293 May 28 3:00 PM - 4:30 PM

PURPOSE: This double-blind placebo-controlled study investigated the effects of resistance training (RT), with and without protein supplementation (PRO), on body composition, muscle strength and physical function in long term Roux-en-Y bypass (RYGB) female patients. METHODS: A total of 45 women (age 40.4 ± 8.5 yrs, BMI 29.0 ± 4.7 kg/m2) with 4.1 ± 1.4 yrs after RYGB surgery were divided into four groups: Control + Placebo (CON+PL; n = 11), Control + PRO (CON+PRO; n = 10), RT+PL (n = 12), and RT+PRO (n = 12). Patients were evaluated before and after the 12-weeks study protocol for body composition (Tetrapolar Bioelectrical Impedance), knee extensors isokinetic strength and physical function (timed up and go [TUG], 30-seconds sit to stand, and 6-minutes walking). PRO and PL were administrated in a double-blind fashion and respectively consisted of daily 0.5 g of whey protein powder per kg of ideal body weight and an isocaloric placebo powder, both throughout the study period. Training protocol comprised 3 sets of 8-12 reps for 8 exercises targeting all major muscle groups and with progressive loads. ANOVA was used to assess time by group interactions. RESULTS: No significant between-groups differences were observed for any variable at baseline (all P > .05). Significant improvements were observed in the exercised groups, but not in the nonexercised groups, for skeletal muscle mass (RT+PL 0.6 ± 0.3, P = .02; RT+PRO 0.8 ± 0.2, P .05). Also, no significant alteration occurred for percent body fat in any group (all P > .05). CONCLUSIONS: A 12-weeks RT program, regardless of PRO, improves muscle mass, knee extensors isokinetic strength and physical function in long term RYGB female patients.