Optimization of the Antibacterial Activity of Silver Nanoparticles-Decorated Graphene Oxide Nanocomposites

•Ag/GO was successfully synthesized by the in situ method. Glucose was used as an eco-friendly reducing agent.•AgNPs with an average size of 17.68 ± 4.48 nm.•Ag/GO express the extremely high antibacterial capacity against S. aureus and S. enterica.•Placket–Burman and Box–Behnken model experimental design was used to optimize.