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四跨膜蛋白在胃癌中的表达和意义

Nie Xiaofei,Qiu Zhenkang,Liu Ning,Qi Weiwei,Ding Aiping,Qiu Wensheng

Guoji zhongliuxue zazhi（2017）

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Abstract
四跨膜蛋白是一类表达非常广泛的细胞表面糖蛋白,可以与整合素、信号蛋白、生长因子等多种细胞表面分子结合并发挥功能.近年来越来越多的研究提示四跨膜蛋白与恶性肿瘤的侵袭、转移密切相关,并且显示出一定的临床价值,可作为恶性肿瘤诊断和预后的新指标.
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Key words
Stomach neoplasms,Prognosis,Tetraspanins
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