Deep learning reconstruction of equilibrium phase CT images in obese patients

Purpose: To compare abdominal equilibrium phase (EP) CT images of obese and non-obese patients to identify the reconstruction method that preserves the diagnostic value of images obtained in obese patients. Methods: We compared EP images of 50 obese patients whose body mass index (BMI) exceeded 25 (group 1) with EP images of 50 non-obese patients (BMI < 25, group 2). Group 1 images were subjected to deep learning reconstruction (DLR), hybrid iterative reconstruction (hybrid-IR), and model-based IR (MBIR), group 2 images to hybrid-IR; group 2 hybrid-IR images served as the reference standard. A radiologist recorded the standard deviation of attenuation in the paraspinal muscle as the image noise. The overall image quality was assessed by 3 other radiologists; they used a confidence scale ranging from 1 (unacceptable) to 5 (excellent). Non-inferiority and potential superiority were assessed. Results: With respect to the image noise, group 1 DLR- were superior to group 2 hybrid-IR images; group 1 hybrid-IR- and MBIR images were neither superior nor non-inferior to group 2 hybrid-IR images. The quality scores of only DLR images in group 1 were superior to hybrid-IR images of group 2 while the quality scores of group 1 hybrid-IR- and MBIR images were neither superior nor non-inferior to group 2 hybrid-IR images. Conclusions: DLR preserved the quality of EP images obtained in obese patients.