Molecular Mechanism of a Novel GluN 1 Glycine-Site Antagonist ! " ! ! Crystal Structure and Pharmacological Characterization of a Novel NMDA Receptor Antagonist at the GluN 1 Glycine Binding Site
semanticscholar(2013)
摘要
From Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark. Schrödinger, Inc. 120 West 45 St., New York, NY 10036, USA. Department of Pharmacology, Emory University School of Medicine, Rollins Research Center, 1510 Clifton Road, Atlanta, GA 30322, USA. ! Running title: Molecular Mechanism of a Novel GluN1 Glycine-Site Antagonist ! To whom correspondence should be addressed: Hans Bräuner-Osborne, Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Fruebjergvej 3, DK2100 Copenhagen, Denmark, Phone: (+45) 3917 9659, E-mail: hbo@sund.ku.dk !
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