CD8+CD122+ T cell homeostasis is controlled by different levels of IL-15 trans-presentation
Journal of Microbiology, Immunology and Infection（2021）
摘要
The homeostasis of CD8+CD122+ T cell requires IL-15 trans-presentation. We use Il15ra mutant mice and bone marrow chimeras to assess the role of IL-15 trans-presentation level in CD8+CD122+ T cells homeostasis. We demonstrate that CD8+CD122+ T cells require different levels of IL-15 trans-presentation to support their homeostasis.
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关键词
IL-15,CD8+CD122+ T cell homeostasis
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