Stress fibres fuel glycolysis
NATURE REVIEWS MOLECULAR CELL BIOLOGY(2020)
摘要
In cells exposed to stiff extracellular matrix, sequestration of the ubiquitin ligase TRIM21 by actin stress fibres can prevent the ubiquitination and breakdown of the glycolytic enzyme PFK, directly linking mechanical sensing to metabolic regulation.
更多查看译文
关键词
Mechanotransduction,Stress fibres,Life Sciences,general,Cell Biology,Cancer Research,Developmental Biology,Stem Cells,Biochemistry
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要