Itraconazole versus posaconazole for antifungal prophylaxis in patients with acute myeloid leukemia undergoing intensive chemotherapy: a retrospective study.
International Journal of Antimicrobial Agents（2020）
Abstract
•Posaconazole was associated with lower rates of prophylaxis failure compared with itraconazole•Posaconazole showed enhanced tolerability and decreased rates of suspected breakthrough invasive fungal infection (IFI)•Posaconazole recipients were less likely to be discharged on an extended antifungal treatment course
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Key words
Leukemia,Myeloid,Acute,Induction Chemotherapy,Neutropenia,Invasive Fungal Infections,Antifungal Agents,Azoles
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