Synthesis and Evaluation of Bicyclic Hydroxypyridones As Inhibitors of Catechol O-Methyltransferase
Glen Ernst,Daniel Akuma,Vinh Au,Ingrid P. Buchler,Spencer Byers,Gregory V. Carr,Sabine Defays,Pablo de Leon,Thierry Demaude,Michael DePasquale,Veronique Durieu,Yifang Huang,Emilie Jigorel,Martha Kimos,Anna Kolobova,Florian Montel,Florence Moureau,Michael Poslusney,Dominique Swinnen,Marie-Christine Vandergeten,Nathalie Van Houtvin,Huijun Wei,Noelle White,Martyn Wood,James C. Barrow ACS Medicinal Chemistry Letters(2019)
关键词
Catechol O-methyl transferase,catechol mimic,enzyme inhibitors,dopamine metabolism
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