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Elevated blood sugar parameters in young Indian men attending our fertility clinic

FERTILITY AND STERILITY(2019)

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摘要
India is considered the diabetic capital of the world (1). This study aims to review the levels of high blood sugar parameters for the incidence of Type 2 Diabetes in young male partners of Indian couples seeking fertility treatment since there is a paucity of studies documenting blood sugar levels in young Indian men. Retrospective observational study in the young Indian male visiting our Fertility Centre. Over a 6 month period, 727 male partners of Indian ethnicity (median age 35 years, range 24 - 45 years) of couples visiting our fertility clinic for the first time were investigated for blood sugar levels with one or more of the following parameters: a) Fasting plasma glucose (FPG) with no calorie intake for at least 8 hours. b) 2 hours plasma glucose (2 hr PG) during oral glucose tolerance test (OGTT) using a glucose load containing 75 gm glucose. c) Glycosylated Haemoglobin (HbA1C).Tabled 1Criteria by the American Diabetes Association (ADA) for the diagnosis of DiabetesFasting plasma glucose (FPG)2 hrs plasma glucose in OGTTHbA1CDiabetic≥ 126 mg/dl≥ 200 mg/dl≥ 6.5 %Prediabetic≥ 100 - 125 mg/dl≥ 140 - 199 mg/dl≥ 5.7 - 6.4 %Normal< 100 mg/dl< 140 mg/dl< 5.7 % Open table in a new tab Of the 727 young male partners, while 62 (8.5 %) were diabetic, 279 (38.4 %) were prediabetic. The remaining 386 (53.1 %) were normal. Our study found that Indian men showed deranged blood sugar parameters indicating the prevalence of diabetes in young Indian men. Furthermore it highlights the importance of screening male partners prior to fertility treatment. In India, a trend indicates that there is a rapid increase in the number of individuals becoming diabetic and a decline in the mean age of onset of Type 2 Diabetes. This is a disturbing trend as Type 2 Diabetes is seen in Indian males a decade earlier than in Caucasian males (2).
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关键词
blood sugar parameters,fertility,young indian men
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