Research Progress of γδ T Cells in Cancer Immunotherapy

Cancer is the major threat to human health. Traditional treatment, which combines surgery with radiotherapy,chemotherapy and other subsidiary treatments, still faces tremendous challenges to enhance the efficacy and lower the possibility of cancer recurrence. Recently immunotherapy offers a promising option for cancer treatment which evokes broad interest. Innate immune cells, in particular γδ T cells, have become the promising candidates to be adoptively transferred, because of their strong anti-tumor cytotoxicity and synergistic effect with other immune cells. This paper described the new progresses of the γδ T cells in basic research and clinical trials for cancer treatment.