The Influence of a GH Receptor Antagonist (GHRA) on the Relationship Between GH and IGF-I in Adults with Growth Hormone Deficiency (AGHD)

C Berg,A Pokrajac,M Bidlingmaier,C Strasburger,K Mann,SM Shalet,PJ Trainer

Experimental and clinical endocrinology & diabetes（2006）

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摘要

Approximately 50% of patients with severe AGHD (defined by the international consensus criteria, peak GH <3ng/ml) have a normal age- and gender-related IGF-I. It remains unclear whether in these individuals IGF-I is GH-dependent.

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