Estrogen stimulates female cancer progression by inducing myeloid-derived suppressive cells: investigations on pregnant and non-pregnant experimental models.

Katsumi Kozasa,Seiji Mabuchi,Yuri Matsumoto,Hiromasa Kuroda,Eriko Yokoi,Naoko Komura,Mahiru Kawano,Ryoko Takahashi,Tomoyuki Sasano,Kotaro Shimura,Michiko Kodama,Kae Hashimoto,Kenjiro Sawada,Kazunori Nagasaka,Tadashi Kimura

Oncotarget（2019）

引用 21|浏览30

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摘要

E2 facilitates the progression of ERα-negative cervical or breast cancer under non-pregnant and pregnant conditions by inducing MDSC. MDSC inhibition therapy may have therapeutic efficacy in premenopausal or pregnant female cancer patients.

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关键词

MDSC,brest cancer,cervical cancer,estrogen,pregnancy

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