Secretory changes and inflammation are associated with vascular dysfunction in obese patients

Aim: A variety of molecules secreted by white (adipokines) and brown (batokines) adipose tissue, liver (hepatokines) and skeletal muscle (myokines) physiologically participate in the control of energy balance and glucose/lipid metabolism, as well as in the regulation of vascular homeostasis. We tested whether changes in their secretory profile couples with inflammation, insulin resistance and vascular dysfunction in obese patients.