Elucidating opportunities and pitfalls in the treatment of experimental traumatic brain injury to optimize and facilitate clinical translation

Patricia B. de la Tremblaye,Darik A. O’Neil,Megan J. LaPorte,Jeffrey P. Cheng,Joshua A. Beitchman,Theresa Currier Thomas,Corina O. Bondi,Anthony E. Kline

Neuroscience & Biobehavioral Reviews（2018）

引用 25|浏览17

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摘要

•Neurorehabilitation is effective after experimental TBI.•Digging- and operant-based attentional tasks are sensitive measures of executive function after TBI.•CB1 receptors implicated in neuroendocrine stress and plasticity.•Antipsychotic and antiepileptic drugs impair functional recovery.

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关键词

Antiepileptic drugs (AEDs),Antipsychotic drugs (APDs),Controlled cortical impact (CCI),Endocannabinoids,Executive function,Fluid percussion (FP) injury,Morris water maze (MWM),Rehabilitation,Stress,Traumatic brain injury (TBI)

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