Intraarticular Administration of Dobesilate for the Treatment of Knee Rheumatoid Arthritis
MOJ Clinical & Medical Case Reports(2016)
摘要
Rheumatoid arthritis is an inflammatory condition that causes a negative effect in patient well-being. Fibroblast growth factor participates in the pathology of rheumatoid arthritis through its proliferative, inflammatory and angiogenic activities. Dobesilate, an inhibitor of fibroblast growth factor shows marked anti-proliferative, anti-inflammatory, and anti-angiogenic activities. Our study shows that intraarticular application of dobesilate is effective in reducing symptoms and signs in patients with chronic knee rheumatoid arthritis.
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关键词
dobesilate,intraarticular administration,rheumatoid arthritis,knee
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