Association between cholesterol crystals and culprit lesion vulnerability in patients with acute coronary syndrome: An optical coherence tomography study.

•OCT-Cholesterol crystals (ChCs) was associated with culprit lesion vulnerability in patients with acute coronary syndrome (ACS).•ChC plays a critical role in lipid necrotic core formation, local inflammation, and plaque rupture.•ChCs is associated with patients clinical manifestation (STEMI or NSTEACS).