Current Trends of Liver Cirrhosis in Mexico: Similitudes and Differences with Other World Regions

AIM To investigate the main current etiologies of cirrhosis in Mexico.METHODS We performed a cross-sectional retrospective multicenter study that included eight hospitals in different areas of Mexico. These hospitals provide health care to people of diverse social classes. The inclusion criteria were a histological, clinical, biochemical, endoscopic, or imaging diagnosis of liver cirrhosis. Data were obtained during a 5-year period（January 2012-December 2017）. RESULTS A total of 1210 patients were included. The mean age was 62.5 years（SD = 12.1）, and the percentages of men and women were similar（52.0% vs 48.0%）. The most frequent causes of liver cirrhosis were hepatitis C virus（HCV）（36.2%）, alcoholic liver disease（ALD）（31.2%）, and nonalcoholic steatohepatitis（23.2%）, and the least frequent were hepatitis B virus（1.1%）, autoimmune disorders（7.3%）, and other conditions（1.0%）.CONCLUSION HCV and ALD are the most frequent causes of cirrhosis in Mexico. However, we note that non-alcoholic fatty liver disease（NAFLD） as an etiology of cirrhosis increased by 100% compared with the rate noted previously. We conclude that NAFLD will soon become one of the most frequent etiologies of liver cirrhosis in Mexico.