Copper-catalyzed three-component synthesis of pyrimidines from amidines and alcohols
Organic & Biomolecular Chemistry（2018）
摘要
An efficient copper-catalyzed one-pot three-component reaction of amidines, primary alcohols and secondary alcohols has been developed to synthesize multisubstituted pyrimidines. The significant merits of this method involve high atom efficiency, good functional group tolerance and operational simplicity.
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关键词
pyrimidines,amidines,synthesis,copper-catalyzed,three-component
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