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Ginkgolide B enhances gemcitabine sensitivity in pancreatic cancer cell lines via inhibiting PAFR/NF-кB pathway.

Changjie Lou,Haibo Lu,Zhigang Ma,Chao Liu,Yanqiao Zhang

Biomedicine & Pharmacotherapy（2019）

Cited 35|Views18
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Abstract
•Ginkgolide B enhanced gemcitabine sensitivity in pancreatic cancer cell lines.•Ginkgolide B suppressed cell proliferation and increase apoptosis in combination with gemcitabine.•Ginkgolide B increased gemcitabine sensitivity by suppressing PAFR/NF-кB pathway.
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Key words
GB,PAF,PAFR,PI,NF-кB,IC50,IκBα-SR,PBS,IHC,PCNA
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