Epigallocatechin-3-gallate promotes apoptosis and reversal of multidrug resistance in esophageal cancer cells.
Pathology - Research and Practice(2017)
Abstract
•EGCG inhibited cell growth and induced esophageal cancer cell apoptosis.•EGCG modulated bcl-2, bax and caspase-3 protein of esophageal cancer cells.•EGCG reversed multi-drug resistance by reducing ABCG2 expression in cancer cells.
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Key words
Esophageal squamous cell carcinoma,Flow cytometry,Epigallocatechin-3- gallate,Cell apoptosis,Multidrug resistance
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