Influence of glaucoma surgery on the ocular surface using oculus keratograph
International ophthalmology(2018)
摘要
Purpose To investigate the influence of trabeculectomy and phacotrabeculectomy on the ocular surface. Design Retrospective, case–control study. Methods Eighty-one samples without dry eyes were recruited and divided into three groups, including phacoemulsification group ( N = 30) as control group, trabeculectomy group ( N = 27) and phacotrabeculectomy group ( N = 24) as study groups. Ocular surface parameters, including noninvasive keratograph first (NifBUT) and average (NiaBUT) tear film breakup time, tear meniscus height (TMH) and corneal fluorescein stain (CFS), were estimated preoperatively, at 3 days, 1 month and 3 months postoperatively using oculus keratograph. Results No significant difference was observed in ocular surface parameters at baseline among three groups ( p > 0.05). The magnitude of NifBUT and NiaBUT was reduced at 3 days and 1 month postoperatively in phacotrabeculectomy group, but greater than that in the other two groups (All p < 0.001). In all the groups, both the NifBUT and NiaBUT tended to recover at 1 and 3 months postoperatively, whereas both of them did not recover to baseline at 3 months postoperatively in trabeculectomy (NifBUT, p = 0.001; NiaBUT, p < 0.001) and phacotrabeculectomy group (NifBUT, p < 0.001; NiaBUT, p = 0.020). TMH was raised at 3 days postoperatively and restored to the baseline level at 1 and 3 months postoperatively for three groups ( p > 0.05). CFS was elevated at 3 days postoperatively and different in recovery at 1 and 3 months postoperatively for three groups. Conclusions The influence of phacotrabeculectomy on ocular surface is worse than that of trabeculectomy for the short run and is not distinct different for a long time.
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关键词
Glaucoma,Dry eye,Ocular surface,Breakup time,Oculus keratograph
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