Involvements of p38 MAPK and oxidative stress in the ozone-induced enhancement of AHR and pulmonary inflammation in an allergic asthma model
Respiratory Research(2017)
摘要
Exposure to ambient ozone (O3) increases the susceptivity to allergens and triggers exacerbations in patients with asthma. However, the detailed mechanisms of action for O3 to trigger asthma exacerbations are still unclear.
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关键词
Asthma exacerbation,Ozone,p38 MAPK,Oxidative stress,α-tocopherol
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