Binding interactions of halogenated bisphenol A with mouse PPARα: In vitro investigation and molecular dynamics simulation.

•Interaction of halogenated BPAs with mPPARα-LBD* was investigated.•Halogenated BPAs are affinity ligands for mPPARα-LBD*.•The electronic properties varied with the halogenation patterns.•The binding modes were illustrated by molecular docking.•This work can be used for preliminary screening of halogenated BPAs.