The Discovery of Benzoxazine Sulfonamide Inhibitors of Na V 1.7: Tools That Bridge Efficacy and Target Engagement
Daniel S. La,Emily A. Peterson,Christiane Bode,Alessandro A. Boezio,Howard Bregman,Margaret Y. Chu-Moyer,James Coats,Erin F. DiMauro,Thomas A. Dineen,Bingfan Du,Hua Gao,Russell Graceffa,Hakan Gunaydin,Angel Guzman-Perez,Robert Fremeau,Xin Huang,Christopher Ilch,Thomas J. Kornecook,Charles Kreiman,Joseph Ligutti,Min-Hwa Jasmine Lin,Jeff S. McDermott,Isaac Marx,David J. Matson,Stefan I. McDonough,Bryan D. Moyer,Hanh Nho Nguyen,Kristin Taborn,Violeta Yu,Matthew M. Weiss Bioorganic & medicinal chemistry letters（2017）
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Medicinal chemistry,Nav1.7,Pharmacology,Structure activity relationship
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