P25: Effect of distal heme pocket mutations on neuroglobin nitrite reduction rates

Neuroglobin is a highly conserved hemoprotein of uncertain physiological function that evolved from a common ancestor to hemoglobin and myoglobin. Unlike hemoglobin or myoglobin, which show a five-coordinate heme iron, neuroglobin shows a six-coordinate heme with proximal and distal histidines in the heme pocket directly bound to the heme iron.