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The use of biologic agents and clinical trials may prolong survival for women with primary platinum resistant ovarian carcinoma

Gynecologic Oncology(2013)

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摘要
Hispanic (8%), Asian (4%), and other races (3%). 29% were from the South, 26% from the Midwest, 25% Northeast, and 21% were from the West. 23% of hospitals were higher volume (N20 cases/year) vs. lower volume hospitals. 1647 (25%) underwent robotic surgery (RS), 820 (12%) laparoscopic (LS), vs. 4093 (62%) had open surgery (OS). The older (N 62 years, median) were more likely to have RS compared to younger (26% vs. 24%, p = 0.02). 29% of Whites had RS compared to only 20% Native Americans, 15% Hispanics, 12% Blacks, and 11% of Asians (p b 0.01). Patients from Midwest, Northeast, South and West had RS in 26%, 26%, 25%, and 23% of cases. Higher volume hospital performed 72% of all surgeries and 84% of all RS. Moreover, these higher volume hospitals were more likely to use RS compared to lower volume institutions (29% vs. 14%, p b 0.01). Those with low(b$40,999),middle ($41,000–$50,999), upper middle ($51,000–$66,999), and high (N$67,000) socioeconomic had RS in 21%, 25%, 28%, and 27% of cases (p b 0.01). Those with Medicare orprivate insurance were more likelyto receive RS at 27% and 26% vs. 14% of Medicaid patients (p b 0.01). Conclusions: In this nationwide analysis of endometrial cancer patients, older, Whites, higher socioeconomic class, receiving care from higher volume hospitals were associated with likelihood of receiving robotic surgery. Further studies are warranted to better understand the barriers of receiving robotic surgery.
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clinical trials,primary platinum,carcinoma,biologic agents
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