358 A Multi-arm Phase 1 Dose Escalation Study of Safety, Pharmacokinetics, and Pharmacodynamics of the Dual PI3K/mTOR Inhibitors PF-04691502 (oral) and PF-05212384 (IV) in Combination with the MEK Inhibitor PD-0325901 or Irinotecan in Patients with Advanced Cancer
European Journal of Cancer(2012)
关键词
pharmacokinetics,inhibitors,dual pi3k/mtor,pharmacodynamics,advanced cancer,multi-arm
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