GENETIC CETP DEFICIENCY ASSOCIATED WITH LOWER CORONARY STENOSIS INDEX IN DYSLIPDEMIC PATIENTS IN JAPAN

Objectives: It is still controversial whether lower CETP is anti-atherogenic or not. Genetic deficiency should have greater impact on clinical course because its lifetime long effect. We evaluated impact of CETP deficiency on coronary atherosclerosis among dyslipidemic patients with non-familial hypercholesterolemia (non-FH) and with FH in Japanese population that include approximately 10% of heterozygous CETP deficiency.