Insights into the structure of the diiron site of RIC from Escherichia coli.

Lígia S Nobre,Diana Lousa,Isabel Pacheco,Cláudio M Soares,Miguel Teixeira,Lígia M Saraiva

FEBS Letters（2015）

Cited 7|Views20

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Abstract

•Structural model of the E. coli RIC diiron centre is presented.•Conserved residues H84, H129, H160, H204, E133 and E208 are ligands of the diiron centre.•Residues E133 and E208 form two μ-carboxylate bridges essential for RIC assembly.

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Key words

RIC,Diiron,Nitrosative and oxidative stress,Iron repair,Iron–sulphur

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