High-level azithromycin-resistant Neisseria gonorrhoeae clinical isolate in France, March 2014.
EUROSURVEILLANCE(2014)
摘要
We report the first case in France of a high-level azithromycin- resistant Neisseria gonorrhoeae (minimum inhibitory concentration (MIC) = 96 mg/L) assigned to MLST7363 (NG-MAST ST6360), also resistant to ciprofloxacin and tetracycline but susceptible to ceftriax-one. The patient was a 51 year-old heterosexual man who returned following 1g azithromycin monotherapy. Mechanisms of azithromycin resistance were a C2599T mutation in the four copies of the rrl gene and a novel mutation in the promoter of the mtrR gene.
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关键词
clinical isolate,high-level,azithromycin-resistant
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