Benzimidazole CB2 agonists: design, synthesis and SAR.

Kausik K Nanda,Darrell A Henze,Kimberly Della Penna,Reshma Desai,Michael Leitl,Wei Lemaire,Rebecca B White,Suzie Yeh,Janine N Brouillette,George D Hartman,Mark T Bilodeau,B Wesley Trotter

Bioorganic & Medicinal Chemistry Letters（2014）

引用 19|浏览21

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摘要

A new series of CB2-selective agonists containing a benzimidazole core is reported. Design, synthesis, SAR and pharmacokinetic data for selected compounds are described.

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关键词

CB2 agonist,Cannabinoid 2 receptor,Benzimidazole

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