A multicellular view of cytokinesis in epithelial tissue.
Trends in Cell Biology(2014)
摘要
•Cytokinesis in epithelial tissues needs to counteract the tension imposed by surrounding epithelial cells.•Cytokinetic ring constriction is sensed by neighboring cells and acts as a mechanical signal to remodel AJs.•Apical midbody formation on asymmetric or symmetric furrowing regulates the planar and apical–basal organization of epithelia.•Cytokinesis in epithelia is a multicellular process.
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关键词
epithelial polarity,adherens junction,E-Cadherin,actin,Myosin II
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