Genetic Polymorphism of Cytochrome P450 (CYP) 1A1, CYP1A2, and CYP2E1 Genes Modulate Susceptibility to Gastric Cancer in Patients with Helicobacter Pylori Infection.
Gastric cancer(2013)
摘要
Activity of cytochrome P450 (CYP), a polymorphic carcinogen-activating enzyme, is exaggerated following Helicobacter pylori infection. We studied the role of CYP2E1, CYP1A2 (rs762551), and CYP1A1 (rs4646903) polymorphisms in association with H. pylori infection in gastric carcinogenesis.
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关键词
Genetic polymorphism,Helicobacter pylori,Gastric cancer,Peptic ulcer,Functional dyspepsia
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