Study Of Lipid-Lowering Action Of Choloxin And Nilevar In Patients With Chronic Renal-Failure
POSTGRADUATE MEDICAL JOURNAL(1974)
摘要
Summary Lowering of lipids in patients with chronic renal failure is advantageous but cannot be done by calorie restriction. In a controlled study the anabolic steroid norethandrolone (Nilevar) was found to lower triglycerides by 50%, while D-thyroxine (Choloxin) lowered the cholesterol by 25%. Both drugs increased the activity of lipoprotein lipase in spite of uraemic inhibition. Norethandrolone also reduced basal serum insulin levels. Norethandrolone seems appropriate for underweight patients and D-thyroxine for overweight patients, but side effects are more frequent than in non-uraemic patients.
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关键词
lipoprotein lipase,side effect
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