Site-directed delivery of nitric oxide to cancers.

Nitric Oxide（2014）

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摘要

•Strategies for enzyme activated nitric oxide generation are discussed.•Nitric oxide prodrugs targeting cancers are reviewed.•NO-based hybrid drugs can help overcome drug resistance in cancers.

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关键词

Diazeniumdiolate,Prodrug,Drug delivery,Enzyme,Glutathione

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