Improving the Sensitivity of Surface Plasmon Resonance Phase Imaging System
Sensor letters(2011)
摘要
Improving sensitivity is crucial for high-throughput surface plasmon resonance (SPR) array detection. In our experiment setup, CCD camera is used as the array detector. Experiment results indicate that the camera's noise is a main factor affecting the detection sensitivity. This article presents several effective ways to improve the sensitivity of the SPR phase imaging system. 1.0 x 10(-6) refractive index unit (RIU) resolution can be achieved for a 300 x 300 mu m(2) reaction area by decreasing the camera noise. The sensitivity could be further increased similar to 35% by changing the exposure times periodically during the image acquisition, which can also get as much as 4 times of the original spatial resolution.
更多查看译文
关键词
Surface Plasmon Resonance (SPR),Time Domain Modulation Interferometry,Sensitivity,CCD Noise
AI 理解论文
溯源树
样例
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要