Characterization of the components of meleumycin by liquid chromatography with photo-diode array detection and electrospray ionization tandem mass spectrometry.
Journal of Pharmaceutical and Biomedical Analysis(2013)
摘要
•The impurity profiling of meleumycin were characterized by LC/PDA/ESI-MS/MS.•Twelve impurities that had never been reported before were identified.•Twelve others were partially characterized.
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关键词
Liquid chromatography–mass spectrometry,Photo-diode array detection,Meleumycin,Component identification,Macrolide antibiotic
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